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ea0041ep796 | Obesity | ECE2016

Decrease in arterial stiffness (AS) in morbidly obese (MO) patients after bariatric surgery (BS): Relationship with obstructive sleep apnoea (OSA), anthropometric parameters and low-grade inflammation (LGI)

Caixas Assumpta , Tirado Raquel , Vigil Laura , Jose Masdeu Maria , Villaplana Maria , Luna Alexis , Rebassa Pere , Hurtado Marta , Pareja Rocio , Pons Belen , Rigla Mercedes

Materials and methods: We studied 30 MO patients with OSA without Continuous Positive Airway Pressure (CPAP) treatment, before and one year after surgery. All patients underwent overnight conventional polisomnography (CE-Series Compumedics, Victoria, Australia). Sleeve gastrectomy or Roux-en-Y gastric bypass were performed according to the local protocol. To asses AS, augmentation index adjusted for heart rate (IAx@75) was obtained by applanation tonometry (Sphygmocor&#17...

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ea0041ep797 | Obesity | ECE2016

Relationship between the severity of obstructive sleep apnoea (OSA), low-grade-inflammation (LGI) and Heme Oxygenase 1 (HO1) in morbidly obese (MO) patients, before and after bariatric surgery (BS)

Tirado Raquel , Jose Masdeu Maria , Vigil Laura , Rebassa Pere , Luna Alexis , Montmany Sandra , Villaplana Maria , Pons Belen , Rigla Mercedes , Caixas Assumpta

Introduction: HO1 is a new adipokine with a protective role against cellular stress and hypoxia1. MO presents with high low grade inflammation (LGI)2 and high circulating levels or adipose tissue expression of HO13. The effect of bariatric surgery on HO1 and its relationship with OSA and LGI has not yet been studied.Methods: We studied 66 MO patients before and 1 year after BS. All of them presented OSA without Continuous...

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Endocrine Abstracts

Decrease in arterial stiffness (AS) in morbidly obese (MO) patients after bariatric surgery (BS): Relationship with obstructive sleep apnoea (OSA), anthropometric parameters and low-grade inflammation (LGI)

Relationship between the severity of obstructive sleep apnoea (OSA), low-grade-inflammation (LGI) and Heme Oxygenase 1 (HO1) in morbidly obese (MO) patients, before and after bariatric surgery (BS)

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